杨仕平
发布人:信息发布员  发布时间:2017-04-24   浏览次数:4455

  

 

  

1. 个人简介:

杨仕平博士,教授,无机化学与生物化工专业硕士生导师,环境化学博士生导师。

教育经历:

1997-2000,博士,中山大学

1991-1994,硕士,郑州大学

工作经历:

2004-至今,上海师范大学教授

2002-2004,上海师范大学副教授

2000-2002,华南农业大学博士后

2. 主要研究方向:

生物无机化学、纳米材料生物应用以及功能配合物应用。主要以多功能材料为平台,开发面对肿瘤精准医疗的影像探针和诊疗一体化试剂。

[1] 磁、光纳米材料在医学成像、水处理,特别是在疾病的早期诊断上的应用;

[2] 磁传感器及其在过渡金属离子、生物大分子和微生物学等方面的应用;

[3] 咪唑基团配位聚合物及其纳米材料的结构分析和应用。

3. 代表性科研项目:

[1] 基于超小Fe@Fe3O4纳米粒子的T1磁共振成像研究,国家自然科学基金(面上项目),2017-2020

[2] 基于Gd标记的磁性纳米粒子的合成及其在肿瘤靶向MRI中的应用,国家自然科学基金(面上项目),2013-2016

[3] 重金属离子检测的磁性微球开发,上海市科委科技攻关项目,2013-2016

[4] 基于PAMAM 原位修饰的功能化铁酸锰的合成及其在分子影像中的应用,国家自然科学基金(面上项目),2010-2012

4. 代表性论文及著作:

[1] Lu An, Xiaodong Wang, Xichuan Rui, Jiaomin Lin, Hong Yang, Qiwei Tian*, Cheng Tao, Shiping Yang*. In situ sulfidation of Cu2O by endogenous H2S for colon cancer theranostics. Angewandte Chemie (International ed. in English), 2018.

[2] Lu An, Chenglin Yan, Xueling Mu, Cheng Tao, Qiwei Tian*, Jiaomin Lin, Shiping Yang*. Paclitaxel-Induced Ultrasmall Gallic Acid-Fe@BSA Self-Assembly with Enhanced MRI Performance and Tumor Accumulation for Cancer Theranostics. ACS Appl. Mater. Interfaces, 2018, 10 (34), 28483-28493.

[3] Qunfeng Feng, Yanjun Xu, Bing Hu, Lu An, Jiaomin Lin, Qiwei Tian*, Shiping Yang*. A smart off-on copper sulfide photoacoustic imaging agent based on amorphous-crystalline transition for cancer imaging. Chem. Commun., 2018, 54 (78), 10962-10965.

[4] Ping Zhou, Heng Zhao, Quan Wang, Zhiguo Zhou*, Jing Wang, Guang Deng, Xiyou Wang, Qian Liu, Hong Yang, Shiping Yang*. Photoacoustic-Enabled Self-Guidance in Magnetic-Hyperthermia Fe@Fe3O4 Nanoparticles for Theranostics In Vivo. Advanced Healthcare Materials, 2018, 7 (9).

[5] Heng Zhao, Ping Zhou, Kai Huang, Guang Deng, Zhiguo Zhou*, Jing Wang, Mingwei Wang, Yingjian Zhang*, Hong Yang, Shiping Yang*. Amplifying Apoptosis Homing Nanoplatform for Tumor Theranostics. Advanced Healthcare Materials, 2018, 7 (14).

[6] Jing Wang, Heng Zhao, Zhiguo Zhou*, Ping Zhou, Yuping Yan, Mingwei Wang*, Hong Yang, Yingjian Zhang, Shiping Yang*. MR/SPECT Imaging Guided Photothermal Therapy of Tumor-Targeting Fe@Fe3O4 Nanoparticles in Vivo with Low Mononuclear Phagocyte Uptake. ACS Appl. Mater. Interfaces, 2016, 8 (31), 19872-19882.

[7] Hao Zhang, Huixia Wu*, Jun Wang, Yan Yang, Dongmei Wu, Yingjian Zhang, Yang Zhang, Zhiguo Zhou, Shiping Yang*, Graphene oxide-BaGdF5 nanocomposites for multi-modal imaging and photothermal therapy. Biomaterials 2015, 42, 66-77.

[8] Hong Yang, Changyuan Qin, Chao Yu, Yang Lu, Hongwei Zhang, Fengfeng Xue, Dongmei Wu, Zhiguo Zhou, Shiping Yang*. RGD-Conjugated Nanoscale Coordination Polymers for Targeted T-1- and T-2-weighted Magnetic Resonance Imaging of Tumors in Vivo. Adv. Funct. Mater., 2014, 24 (12), 1738-1747.

[9] Lu An, He Hu*, Jing Du, Jie Wei, Li Wang, Hong Yang, Dongmei Wu, Haili Shi, Fenghua Li, Shiping Yang*. Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging. Biomaterials, 2014, 35 (20), 5381-5392.

[10] Zhiguo Zhou, Yanan Sun, Jinchao Shen, Jie Wei, Chao Yu, Bin Kong, Wei Liu, Hong Yang, Shiping Yang*, Wei Wang*. Iron/iron oxide core/shell nanoparticles for magnetic targeting MRI and near-infrared photothermal therapy. Biomaterials, 2014, 35 (26), 7470-7478.

5. 获奖情况

[1] 上海市自然科学奖三等奖,2018年。

[2] 上海市基础教育教学成果奖一等奖,2017年。

[3]上海科普教育创新奖三等奖,2015年。

[4] 宝钢优秀教师奖,2012年。

6. 代表性授权专利:

[1] 杨仕平,杨艳,杨红,叠氮多巴胺和羧基聚乙二醇修饰的Fe/Fe3O4纳米粒子及其制备和应用,专利号:ZL201610077270.1

[2] 杨仕平,沈金超,杨红,周治国,张钖,杨艳,基于Au-Fe3O4复合纳米粒子的三聚氰胺双模式传感器及制备,专利号:ZL201510155441.3

[3] 杨仕平,孙亚楠,周治国,沈金超,王俊,王力,一种具有光热功能的Fe@Fe3O4纳米粒子及其制备方法和应用,专利号:ZL201310214554.7

[4] 杨仕平,汪娟娟,周治国,陈冬梅,杨昕仪,孔斌,T1-T1协同作用钆螯合四氧化三锰纳米粒子的制备方法及其生物应用,专利号:ZL201210452070.1

  

更新于2018年11月