赵宝国

发布者:信息发布员发布时间:2022-03-16浏览次数:1936


1. 个人简介:

姓名:赵宝国

职称:教授

邮箱:zhaobg2006@shnu.edu.cn

简介:赵宝国 (Dr. Baoguo Zhao) 博士,教授,博士生导师,有机化学专业。主要从事仿生不对称催化和功能分子仿生合成的研究。

2. 教育工作经历:

教育经历:

   2003-2006,博士,中国科学院上海有机化学研究所

   1999-2002,硕士,南京大学

   1992-1996学士,武汉大学

工作经历:

 2011-至今,上海师范大学  教授

 2006-2011,美国科罗拉多州立大学  博士后

3. 研究领域

 [1] 仿生不对称催化

 [2] 仿生全合成

 [3]新反应发展

4. 成果

代表性论文:

[1]Jianfeng Chen,1,2‡ Xing Gong,1‡ Jianyu Li,1 Yingkun Li,1 Jiguo Ma,1 Chengkang Hou,1 Guoqing Zhao,1 Weicheng Yuan,2*Baoguo Zhao1* “Carbonyl Catalysis Enables a Biomimetic Asymmetric Mannich Reaction” Science2018, 360, 1438. (‡equally contributed).

[2]Jiguo Ma, Bin Gao, Guanshui Song, Ruixin Zhang, Qingfang Wang, Zi Ye, Wen-Wen Chen,* Baoguo Zhao* Asymmetric-Allylation of Glycinate with Switched Chemoselectivity Enabled by Customized Bifunctional Pyridoxal Catalysts. Angew. Chem., Int. Ed.2022, 10.1002/anie.202200850. (‡equally contributed).

[3]Bingfei Peng, Jiguo Ma, Jianhua Guo, Yating Gong, Ronghao Wang, Yi Zhang, Jinlong Zeng, Wen-Wen Chen,* Kuiling Ding,* Baoguo Zhao* A Powerful Chiral Super Brønsted C–H Acid for Asymmetric Catalysis. J. Am. Chem. Soc.2022, 144, 2853. (‡equally contributed).

[4]Aolin Cheng, Liangliang Zhang, Qinghai Zhou, Tao Liu, Jing Cao, Guoqing Zhao,* Kun Zhang, Guanshui Song, Baoguo Zhao* Efficient Asymmetric Biomimetic Aldol Reaction of Glycinates and Trifluoromethyl Ketones by Carbonyl Catalysis. Angew. Chem., Int. Ed.2021, 60, 20166.

[5]Jiguo Ma, Qinghai Zhou, Guanshui Song,Y ongchang Song, Guoqing Zhao, Kuiling Ding, Baoguo Zhao* Enantioselective Synthesis of Pyroglutamic Acid Esters from Glycinate via Carbonyl Catalysis. Angew. Chem., Int. Ed. 2021, 60, 10588.

[6]Weiqi Cai, Xuelong Qiao, Hao Zhang, Bo Li, Jianhua Guo, Liangliang Zhang, Wen-Wen Chen, Baoguo Zhao* Asymmetric biomimetic transamination of α-keto amides to peptides. Nat. Commun.2021, 12, 5174.

[7]Yong Ethan Liu, Zhaole Lu, Bo Li, Jiaxin Tian, Feng Liu, Junyu Zhao, Chengkang Hou, Yingkun Li, Lili Niu, Baoguo Zhao* “Enzyme-Inspired Axially Chiral Pyridoxamines Armed with a Cooperative Lateral Amine Chain for Enantioselective Biomimetic TransaminationJ. Am. Chem. Soc. 2016, 138, 10730.

[8] Limin Shi, Chuangan Tao, Qin Yang, Yong Ethan Liu, Jing Chen, Jianfeng Chen, Jiaxin Tian, Feng Liu, Bo Li, Yongling Du, Baoguo Zhao* “Chiral Pyridoxal-Catalyzed Asymmetric Biomimetic Transamination of α-Keto Acids” Org. Lett.2015, 17, 5784.

[9]Lei Ding, Jing Chen, Yifan Hu, Juan Xu, Xing Gong, Dongfang Xu, Baoguo Zhao*, Hexing Li “Aminative Umpolung of Aldehydes to α-Amimo Anion Equivalents for Pd-catalyzed Allyation: An Efficient Synthesis of Homoallylic Amines” Org. Lett.2014, 16, 720.

[10]Baoguo Zhao, Zhaobin Han, Kuiling Ding* “N-H Functions in Organometallic Catalysis” Angew. Chem. Int. Ed.2013, 52, 4744.

代表性授权专利:

[1]赵宝国,刘勇,卢兆乐,李波,“一种手性联芳骨架吡哆胺类催化剂及其合成方法与应用”,申请号:201610444057.X

[2]赵宝国,陈剑锋,赵濬宇,龚幸,“一种新型手性开链吡哆胺催化剂及其合成方法与应用”,专利号:201610444112.5

[3]赵宝国,兰晓宇,陶创安,刘旭亮,“一种手性吡哆胺催化剂及其合成方法和应用”,专利号:201610443128.4

[4] 赵宝国,陈静,石力敏,刘勇,杨琴,陈剑锋,田家昕,陶创安,李波,许东芳“一种新型吡哆素衍生物及其制备方法”,专利号201510413900.3

[5] 赵宝国,陈静,杨琴,陈剑锋,石力敏,刘勇(Yong Ethan Liu),龚幸,兰晓宇,卢兆乐,刘勇 (Yong Liu),陶创安,田家昕,许东芳,“一种吡哆醛催化剂及其合成方法与应用”,专利号:201510415046.4

[6] 赵宝国,陶创安,石力敏,刘勇,陈静,“一种手性吡哆醛催化剂及其合成方法与应用”,专利号:201510427177.4