肖晓

发布者:信息发布员发布时间:2025-09-12浏览次数:11


1. 个人简介:

姓名:肖晓

职称:特聘教授

邮箱:xxiao1207@shnu.edu.cn

简介:博士,有机化学博士生导师,近年来致力于仿生不对称合成, 有机小分子催化等领域的教学科研工作。在Nat. Catal., J. Am. Chem. Soc., Angew. Chem. Int. Ed.等学术刊物上发表SCI论文十余篇,论文被他引>600次。2021加入上海师范大学,被聘为上海市特聘教授。

2. 教育工作经历:

教育经历:

 2007-2012,博士,中国科学院化学研究所

 2003-2007学士,四川大学

工作经历:

 2021-至今,上海师范大学  特聘教授

 2017-2020美国天普大学 博士后研究员

 2012-2017, 沈阳药科大学讲师

3. 研究领域

 [1]仿生不对称合成

 [2]有机小分子催化

 [3]新合成方法学研究

4. 项目与荣誉

  • 国家自然科学基金(面上项目)2025

  • 国家重点研发计划催化专项子课题2023

  • 上海市特聘教授2021

  • 国家自然科学基金(青年项目)2014

  • 教育部高等学校博士学科点专项科研基金2013

5. 成果

代表性论文:

[1]Liang, H.; Ren, P.; Wang, L.; Cai, D.; Gong, S.; Liu, S.; Xiao, X*.; Ding, K.; Zhao B*., “Asymmetric Biomimetic Aldol Reaction of Glycinate Enables Highly Efficient Synthesis of Chiral -Hydroxy-α-Amino Acid Derivatives.” Nat. Catal. 2025, 8, 668-677.

[2]Shi, Z.; Wu, T.; Huang, L.; Liu, S.;Xiao, X*.; Zhao, B*., “Direct Enantioselective Allylic Alkylation of α Amino Esters to Quaternary Glutamates via Strategic Pyridoxal Catalyst Design.” J. Am. Chem. Soc.2025,147, 14945-14953.

[3] Liang, H.;  Cao, J.;  Zhang, H.;  Huang, L.;  Liu, S.;  Wu, T.;  Xiao, X*.; Zhao, B*., “Direct asymmetric α-C–H functionalization of N-unprotected allylamine catalyzed by chiral pyridoxal.” Green Chem. 2025,27, 1374-1380.

[4]Xiao, X.; Zhao, B*., “Vitamin B6-Based Biomimetic Asymmetric Catalysis.Acc. Chem. Res. 2023, 56, 1097-1117.

[5]Xiao, X.; Xu, K.; Gao, Z.-H.; Zhu, Z.-H.; Ye, C.; Zhao, B.; Luo, S.; Ye, S.; Zhou, Y.-G.; Xu, S.; Zhu, S.-F.; Bao, H.; Sun, W.; Wang, X.; Ding, K., “Biomimetic asymmetric catalysis.” Sci. China Chem. 2023,66, 1553-1633.

[6]Xiao, X.; Roth, J. M.; Greenwood, N. S.; Velopolcek, M. K.; Aguirre, J.; Jalali, M.;  Ariafard, A.; Wengryniuk, S. E., “Bidentate Nitrogen-Ligated I(V) Reagents, Bi(N)-HVIs: Preparation, Stability, Structure, and Reactivity.” J. Org. Chem. 2021,86 , 6566-6576.

[7]Xiao, X.; Wengryniuk, S. E., “Recent Advances in the Selective Oxidative Dearomatization of Phenols to o-Quinones and o-Quinols with Hypervalent Iodine Reagents.Synlett 2021,32, 752-762.

[8]Xiao, X.; Greenwood, N. S.; Wengryniuk, S. E., “Dearomatization of Electron-Deficient Phenols to ortho-Quinones: Bidentate Nitrogen-Ligated Iodine(V) Reagents.” Angew. Chem. Int. Ed. 2019, 58, 16181-16187.

[9]Zhang, Y.; Ye, W.; Zhang, H.; Xiao, X.*, “A Novel Catalyst-Free Synthesis of 2,2-Diaryl Enamides from Stilbenes via a Nitrene Transfer Reaction.” Eur. J. Org. Chem.2019,2019, 5720-5724

[10]Zhang, Y.; Ye, W.; Leng, X.; He, Y.; Zhang, H.; Xiao, X.*, “Metal-catalyzed formal amidation of alkenes under CO-free condition.” Tetrahedron Lett. 2016,57, 4203-4206

[11]Xiao, X.;  Liu, M.;  Rong, C.;  Xue, F.;  Li, S.;  Xie, Y.; Shi, Y., “An Efficient Asymmetric Biomimetic Transamination of α-Keto Esters to Chiral α-Amino Esters.” Org. Lett. 2012,14, 5270-5273.

[12]Xiao, X.;  Xie, Y.;  Su, C.;  Liu, M.; Shi, Y., Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives. J. Am. Chem. Soc. 2011,133, 12914-12917.

著作

[1]Xiao Xiao, Xinyi Ren1, Baoguo Zhao, and Kuiling Ding “Privileged Catalyst Structures in Organocatalytic Reactions”in Enantioselective Organocatalysis III: Catalysts, Reactions and Applications, Second Edition. Edited by Peter I. Dalko. 2025 WILEY-VCH GmbH

代表性授权专利:

 [1]史一安,肖晓,光活性-氨基酸的合成方法,专利号:201110115979.3